The Neuroscience of Being Human
The Neuroscience of Hormonal Shifts
How perimenopause, testosterone decline, and the changing endocrine landscape of the forties reshape the brain from the inside out
988-word article with 8 Harvard references.
Premium article
The hormonal changes of the forties are not merely reproductive events. They are neurological events, because the hormones that are shifting, principally oestrogen, progesterone, and testosterone, are among the most powerful modulators of brain function that the body produces. This fully referenced article explores the neuroscience of hormonal shifts in the forties, examines how changing hormone levels affect mood, cognition, sleep, and the stress response, and argues that the hormonal transition of midlife is a brain event masquerading as a body event, with consequences that are poorly understood, frequently dismissed, and systematically undertreated.
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